Some DNA reading methods skip whole pages
Re-testing of genetic tests from the three largest laboratories in the United States has shown that full-exom sequencing (reading only protein-coding genes) can miss large DNA fragments. Because of this,…

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Nutritional botulism: causes and symptoms
Botulism is a serious toxic and infectious disease, which, it would seem, remained in the distant nineties, when we ourselves made stewed meat or received canned goods overdue on cards…

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10 reasons to see a reproductologist
When planning a pregnancy, every woman wants her to come as soon as possible and proceed without complications. But sometimes pregnancy, for some reason, does not occur for a long…

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Biologists have studied the way death of cells with damaged DNA

Employees of the Faculty of Fundamental Medicine of Moscow State University named after MV Lomonosov investigated the effect of genotoxic stress on the stability of the genome, as well as various methods of eliminating defective cells. This condition occurs due to a variety of DNA damage and can lead to cell death. This work was supported by the Russian Science Foundation, and the article was published in the prestigious scientific journal Oncogene. Research will help improve cancer treatments.

Ensuring the stability of the genome is necessary for the normal functioning of the cell. Errors in the replication (doubling) of DNA, as well as a variety of external factors: ultraviolet radiation, chemicals, etc., can violate this stability. The very structure of the hereditary material changes in this case – this is called genotoxic stress. It is fraught with the development of cancer and other dangerous diseases. Continue reading

Human cells used to determine carcinogenicity of substances.

Researchers at the Massachusetts Institute of Technology have come up with a new screening method that is faster, easier and more accurate than existing tests, can determine if a particular substance can cause cancer. An article by scientists was published in the journal Nucleic Acids Research.

At present, according to researchers, about 80 thousand chemicals are used in industry. For the vast majority of them, there is very little or no information about carcinogenicity — the ability to cause cancer. Continue reading

Everything is in the smoke: about the “war” around vaping

With the gradual tightening of anti-tobacco legislation in most developed countries, smokers and tobacco companies are increasingly reorienting themselves to electronic means of nicotine delivery and tobacco heating. Indicator.Ru figured out what disputes surround the new technology, what health effects its use may have, and how electronic cigarettes are still better than usual.
Since the first electronic cigarettes appeared on sale in China in 2004, their share in the market of smoking products has been increasing quite rapidly from year to year. According to data for 2018, more than 40 million people are regular users of such devices. Moreover, if the number of smokers on the planet began to decline gradually (now there are just over a billion), the number of vapers continues to grow. The largest markets for electronic cigarettes today in the United States and Great Britain, followed by Germany, France and China, and the total global market is estimated at an impressive $ 20 billion. Continue reading

“On the way to the light”: how to get rid of depression?
Depression is a mental disorder that manifests itself both at the mental and physiological levels. Currently, this disease is considered to be common. According to various studies, about 20% of…

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Thyroid hormones and which tests to take
In this article we will talk about thyroid hormones. I am often approached with problems: “I have very dry skin”, “Why can my hair roll like this?”, “Why are there…

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Created material that excludes tissue rejection during transplantation
Scientists from Russia and the United States have proposed new material for regenerative medicine. The compounds in the composition of this material literally “turn off” the work of enzymes that…

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What we are being treated for: vaccines against the 60-pointed death star
Why rotavirus infection victims die, why the genome of its pathogen looks completely insane for a molecular biologist, can you get vaccinated against rotavirus, if you are an adult, which…

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